Stemming Cancer: Functional Genomics of Cancer Stem Cells in Solid Tumors

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Cancer stem cells (CSCs) are cells that drive tumorigenesis, as well as giving rise to a large population of differentiated progeny that make up the bulk of the tumor, but that lack tumorigenic potential. CSCs have been identified in a variety of human tumors, as assayed by their ability to initiate tumor growth in immunocompromised mice. Further characterization studies have demonstrated that ...

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ژورنال

عنوان ژورنال: Stem Cell Reviews

سال: 2008

ISSN: 1550-8943,1558-6804

DOI: 10.1007/s12015-008-9034-0